Pregnancy-Associated Plasma Protein-A: Its Significance as a Single Biomarker for Adverse Obstetric Outcomes

OBJECTIVES: Low levels of pregnancy-associated plasma protein-A in pregnant women linked to unhealthy placentation and a spectrum maternal fetal complications. Its assessment as single biomarker has the potential identify high-risk pregnancies. This prospective observational study was conducted find correlation between low first trimester pregnancy with various obstetric outcomes establish if it can be used for counseling couples. STUDY DESIGN: The at Base Hospital, Delhi Cantt. Maternal serum were assessed 11 13+6 weeks gestation, converted multiples median patients followed till delivery. recorded terms abortions, development gestational hypertension, diabetes, preeclampsia, placental abruption, growth restriction, demise, neonatal intensive care unit admission, etc., analyzed an association protein-A. RESULTS: showed statistically significant abortion, also adverse like APGAR <5 1 min, perinatal deaths. No observed preterm delivery, abruption. CONCLUSION: Serum have being utilized validated marker outcomes. Early identification such pregnancies help optimizing feto-maternal through closer surveillance, timely intervention, referral tertiary centers. Further research would fraternity developing prediction model.